Original Research

Optimizing Recruitment and Retention in Cancer Clinical Trials in Low-Resource Settings: Barriers and Facilitators From Nigerian Provider's Perspectives

Olakunde BO, Idemili-Aronu N, Friebel-Klingner TM, et al.

Abstract

The underrepresentation of African countries in cancer clinical trials continues to widen global cancer health disparities. This convergent parallel mixed-methods study assessed healthcare providers' perspectives on recruitment and retention in cancer clinical trials, drawing on a survey and focus group discussions with providers from the ICON-3 Practice-Based Research Network across Nigeria's six geopolitical zones. Among 35 survey respondents and 25 focus group participants, the most cited patient-related barriers were limited understanding of clinical trials, cultural barriers, and lack of financial compensation for visits, while provider-related barriers included negative staff attitudes, inadequate training in good clinical practice, and heavy clinical workload. Friendliness of the study team and clarity of trial information were rated as the most important facilitators, highlighting the need for culturally appropriate recruitment strategies.

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Citation Details

Journal Journal of Clinical Oncology Global Oncology
Year 2025
Authors Olakunde BO, Idemili-Aronu N, Friebel-Klingner TM, et al.
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